ea0028oc3.2 | Obesity, thyroid and Addison's disease | SFEBES2012
Harte Alison
, Varma Madhusudhan
, Tripathi Gyanendra
, McGee Kirsty
, Al-Daghri Nasser
, Al-Attas Omar
, Sabico Shaun
, O'Hare Joseph
, Ceriello Antonio
, Saravanan Ponnusamy
, Kumar Sudhesh
, McTernan Philip
Habitual post-prandial absorption of saturated fatty acids (SFAs) increases systemic atherogenic lipoproteins and a pro-inflammatory response, a condition exacerbated by obesity, insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Also, gut derived bacteria (endotoxin) is absorbed coupled to damaging lipoproteins as it crosses the mucosa, which could directly impact on adipose tissue, as our previous studies suggest. The current studies addressed whether a SFA rich me...